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Age-dependency of terminal ileum tissue resident memory T cell responsiveness profiles to S. Typhi following oral Ty21a immunization in humans
BACKGROUND: The impact of aging on the immune system is unequivocal and results in an altered immune status termed immunosenescence. In humans, the mechanisms of immunosenescence have been examined almost exclusively in blood. However, most immune cells are present in tissue compartments and exhibit...
Autores principales: | Booth, Jayaum S., Goldberg, Eric, Patil, Seema A., Barnes, Robin S., Greenwald, Bruce D., Sztein, Marcelo B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053564/ https://www.ncbi.nlm.nih.gov/pubmed/33874975 http://dx.doi.org/10.1186/s12979-021-00227-y |
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