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A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function

BACKGROUND AND AIMS: Gallstone disease (cholelithiasis) is a cholesterol-related metabolic disorders with strong familial predisposition. Mitochondrial DNA (mtDNA) variants accumulated during human evolution are associated with some metabolic disorders related to modified mitochondrial function. The...

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Detalles Bibliográficos
Autores principales: Sun, Dayan, Niu, Zhenmin, Zheng, Hong-Xiang, Wu, Fei, Jiang, Liuyiqi, Han, Tian-Quan, Wei, Yang, Wang, Jiucun, Jin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053626/
https://www.ncbi.nlm.nih.gov/pubmed/33279689
http://dx.doi.org/10.1016/j.jcmgh.2020.11.015