Combined α-methylacyl-CoA racemase inhibition and docetaxel treatment reduce cell proliferation and decrease expression of heat shock protein 27 in androgen receptor-variant-7–positive prostate cancer cells

BACKGROUND: Disease progression in castrate-resistant prostate cancer (PCa) is most commonly driven by the reactivation of androgen receptor (AR) signaling and involves AR splice variants including ARV7. MATERIALS AND METHODS: We used the ARV7-positive PCa cell line, 22Rv1, to study the relationship...

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Detalles Bibliográficos
Autores principales: Yoshizawa, Atsuhiko, Takahara, Kiyoshi, Saruta, Masanobu, Zennami, Kenji, Nukaya, Takuhisa, Fukaya, Kosuke, Ichino, Manabu, Fukami, Naohiko, Niimi, Atsuko, Sasaki, Hitomi, Kusaka, Mamoru, Suzuki, Motoshi, Sumitomo, Makoto, Shiroki, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Pacific Prostate Society 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053692/
https://www.ncbi.nlm.nih.gov/pubmed/33912510
http://dx.doi.org/10.1016/j.prnil.2020.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053692/
https://www.ncbi.nlm.nih.gov/pubmed/33912510
http://dx.doi.org/10.1016/j.prnil.2020.07.001

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