CPA-seq reveals small ncRNAs with methylated nucleosides and diverse termini

High-throughput sequencing reveals the complex landscape of small noncoding RNAs (sRNAs). However, it is limited by requiring 5′-monophosphate and 3′-hydroxyl in RNAs for adapter ligation and hindered by methylated nucleosides that interfere with reverse transcription. Here we develop Cap-Clip acid...

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Detalles Bibliográficos
Autores principales: Wang, Heming, Huang, Rong, Li, Ling, Zhu, Junjin, Li, Zhihong, Peng, Chao, Zhuang, Xuran, Lin, Haifan, Shi, Shuo, Huang, Pengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053708/
https://www.ncbi.nlm.nih.gov/pubmed/33867522
http://dx.doi.org/10.1038/s41421-021-00265-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053708/
https://www.ncbi.nlm.nih.gov/pubmed/33867522
http://dx.doi.org/10.1038/s41421-021-00265-2

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