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p67: a cryptic lysosomal hydrolase in Trypanosoma brucei?

p67 is a type I transmembrane glycoprotein of the terminal lysosome of African trypanosomes. Its biosynthesis involves transport of an initial gp100 ER precursor to the lysosome, followed by cleavage to N-terminal (gp32) and C-terminal (gp42) subunits that remain non-covalently associated. p67 knock...

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Detalles Bibliográficos
Autores principales: Koeller, Carolina M., Smith, Terry K., Gulick, Andrew M., Bangs, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053727/
https://www.ncbi.nlm.nih.gov/pubmed/33070788
http://dx.doi.org/10.1017/S003118202000195X