Targeting Hypoxia Using Evofosfamide and Companion Hypoxia Imaging of FMISO-PET in Advanced Biliary Tract Cancer

PURPOSE: Hypoxia is widely known as one of the mechanisms of chemoresistance and as an environmental condition which triggers invasion and metastasis of cancer. Evofosfamide is a hypoxia-activated prodrug of the cytotoxin bromo-isophosphoramide mustard conjugated with 2-nitroimidazole. Biliary tract...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Jeesun, Kang, Seo Young, Lee, Kyung-Hun, Cheon, Gi Jeong, Oh, Do-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053876/
https://www.ncbi.nlm.nih.gov/pubmed/33091966
http://dx.doi.org/10.4143/crt.2020.577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053876/
https://www.ncbi.nlm.nih.gov/pubmed/33091966
http://dx.doi.org/10.4143/crt.2020.577

Ejemplares similares