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Learning the molecular grammar of protein condensates from sequence determinants and embeddings
Intracellular phase separation of proteins into biomolecular condensates is increasingly recognized as a process with a key role in cellular compartmentalization and regulation. Different hypotheses about the parameters that determine the tendency of proteins to form condensates have been proposed,...
Autores principales: | Saar, Kadi L., Morgunov, Alexey S., Qi, Runzhang, Arter, William E., Krainer, Georg, Lee, Alpha A., Knowles, Tuomas P. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053968/ https://www.ncbi.nlm.nih.gov/pubmed/33827920 http://dx.doi.org/10.1073/pnas.2019053118 |
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