Structural basis for Clostridium perfringens enterotoxin targeting of claudins at tight junctions in mammalian gut

The bacterium Clostridium perfringens causes severe, sometimes lethal gastrointestinal disorders in humans, including enteritis and enterotoxemia. Type F strains produce an enterotoxin (CpE) that causes the third most common foodborne illness in the United States. CpE induces gut breakdown by disrup...

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Detalles Bibliográficos
Autores principales: Vecchio, Alex J., Rathnayake, Sewwandi S., Stroud, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053971/
https://www.ncbi.nlm.nih.gov/pubmed/33876770
http://dx.doi.org/10.1073/pnas.2024651118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053971/
https://www.ncbi.nlm.nih.gov/pubmed/33876770
http://dx.doi.org/10.1073/pnas.2024651118

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