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Establishment of heterochromatin in domain-size-dependent bursts

Methylation of histone H3K9 is a hallmark of epigenetic silencing in eukaryotes. Nucleosome modifications often rely on positive feedback where enzymes are recruited by modified nucleosomes. A combination of local and global feedbacks has been proposed to account for some dynamic properties of heter...

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Detalles Bibliográficos
Autores principales: Nickels, Jan Fabio, Edwards, Ashleigh Katrine, Charlton, Sebastian Jespersen, Mortensen, Amanda Møller, Hougaard, Sif Christine Lykke, Trusina, Ala, Sneppen, Kim, Thon, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053981/
https://www.ncbi.nlm.nih.gov/pubmed/33827924
http://dx.doi.org/10.1073/pnas.2022887118