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The giant axolotl genome uncovers the evolution, scaling, and transcriptional control of complex gene loci

Vertebrates harbor recognizably orthologous gene complements but vary 100-fold in genome size. How chromosomal organization scales with genome expansion is unclear, and how acute changes in gene regulation, as during axolotl limb regeneration, occur in the context of a vast genome has remained a rid...

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Detalles Bibliográficos
Autores principales: Schloissnig, Siegfried, Kawaguchi, Akane, Nowoshilow, Sergej, Falcon, Francisco, Otsuki, Leo, Tardivo, Pietro, Timoshevskaya, Nataliya, Keinath, Melissa C., Smith, Jeramiah James, Voss, S. Randal, Tanaka, Elly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053990/
https://www.ncbi.nlm.nih.gov/pubmed/33827918
http://dx.doi.org/10.1073/pnas.2017176118