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The giant axolotl genome uncovers the evolution, scaling, and transcriptional control of complex gene loci
Vertebrates harbor recognizably orthologous gene complements but vary 100-fold in genome size. How chromosomal organization scales with genome expansion is unclear, and how acute changes in gene regulation, as during axolotl limb regeneration, occur in the context of a vast genome has remained a rid...
Autores principales: | Schloissnig, Siegfried, Kawaguchi, Akane, Nowoshilow, Sergej, Falcon, Francisco, Otsuki, Leo, Tardivo, Pietro, Timoshevskaya, Nataliya, Keinath, Melissa C., Smith, Jeramiah James, Voss, S. Randal, Tanaka, Elly M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053990/ https://www.ncbi.nlm.nih.gov/pubmed/33827918 http://dx.doi.org/10.1073/pnas.2017176118 |
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