miR-181a, delivered by hypoxic PTC-secreted exosomes, inhibits DACT2 by downregulating MLL3, leading to YAP-VEGF-mediated angiogenesis

Papillary thyroid cancer (PTC) is the most common type of thyroid cancer, and angiogenesis plays critical roles in its recurrence and metastasis. In this study, we investigated the effects of hypoxia-induced exosomal microRNA-181 (miR-181a) from PTC on tumor growth and angiogenesis. Thyroid-cancer-r...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yingxue, Cen, Aiying, Yang, Yuxian, Ye, Huilin, Li, Jiaying, Liu, Shiliang, Zhao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054101/
https://www.ncbi.nlm.nih.gov/pubmed/33898109
http://dx.doi.org/10.1016/j.omtn.2021.02.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054101/
https://www.ncbi.nlm.nih.gov/pubmed/33898109
http://dx.doi.org/10.1016/j.omtn.2021.02.027

Ejemplares similares