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CDC25B induces cellular senescence and correlates with tumor suppression in a p53-dependent manner

The phosphatase cell division cycle 25B (Cdc25B) regulates cell cycle progression. Increased Cdc25B levels are often detected in cancer cell lines and human cancers and have been implicated in contributing to tumor growth, potentially by providing cancer cells with the ability to bypass checkpoint c...

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Detalles Bibliográficos
Autores principales: Chen, Ying-Chieh, Hsieh, Hsi-Hsien, Chang, Hsi-Chi, Wang, Hsin-Chiao, Lin, Wey-Jinq, Lin, Jing-Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054198/
https://www.ncbi.nlm.nih.gov/pubmed/33745968
http://dx.doi.org/10.1016/j.jbc.2021.100564