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CDC25B induces cellular senescence and correlates with tumor suppression in a p53-dependent manner
The phosphatase cell division cycle 25B (Cdc25B) regulates cell cycle progression. Increased Cdc25B levels are often detected in cancer cell lines and human cancers and have been implicated in contributing to tumor growth, potentially by providing cancer cells with the ability to bypass checkpoint c...
Autores principales: | Chen, Ying-Chieh, Hsieh, Hsi-Hsien, Chang, Hsi-Chi, Wang, Hsin-Chiao, Lin, Wey-Jinq, Lin, Jing-Jer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054198/ https://www.ncbi.nlm.nih.gov/pubmed/33745968 http://dx.doi.org/10.1016/j.jbc.2021.100564 |
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