Intention-to-treat analysis may be more conservative than per protocol analysis in antibiotic non-inferiority trials: a systematic review

BACKGROUND: In non-inferiority trials, there is a concern that intention-to-treat (ITT) analysis, by including participants who did not receive the planned interventions, may bias towards making the treatment and control arms look similar and lead to mistaken claims of non-inferiority. In contrast,...

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Detalles Bibliográficos
Autores principales: Bai, Anthony D., Komorowski, Adam S., Lo, Carson K. L., Tandon, Pranav, Li, Xena X., Mokashi, Vaibhav, Cvetkovic, Anna, Findlater, Aidan, Liang, Laurel, Tomlinson, George, Loeb, Mark, Mertz, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054385/
https://www.ncbi.nlm.nih.gov/pubmed/33874894
http://dx.doi.org/10.1186/s12874-021-01260-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054385/
https://www.ncbi.nlm.nih.gov/pubmed/33874894
http://dx.doi.org/10.1186/s12874-021-01260-7

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