Inhibiting BDNF/TrkB.T1 receptor improves resiniferatoxin-induced postherpetic neuralgia through decreasing ASIC3 signaling in dorsal root ganglia

BACKGROUND: Postherpetic neuralgia (PHN) is a devastating complication after varicella-zoster virus infection. Brain-derived neurotrophic factor (BDNF) has been shown to participate in the pathogenesis of PHN. A truncated isoform of the tropomyosin receptor kinase B (TrkB) receptor TrkB.T1, as a hig...

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Detalles Bibliográficos
Autores principales: Wei, Xiang, Wang, Lina, Hua, Jie, Jin, Xiao-hong, Ji, Fuhai, Peng, Ke, Zhou, Bin, Yang, Jianping, Meng, Xiao-wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054387/
https://www.ncbi.nlm.nih.gov/pubmed/33874962
http://dx.doi.org/10.1186/s12974-021-02148-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054387/
https://www.ncbi.nlm.nih.gov/pubmed/33874962
http://dx.doi.org/10.1186/s12974-021-02148-5

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