CAR-T cells and BiTEs in solid tumors: challenges and perspectives

Chimeric antigen receptor (CAR)-modified T cells and BiTEs are both immunotherapies which redirect T cell specificity against a tumor-specific antigen through the use of antibody fragments. They demonstrated remarkable efficacy in B cell hematologic malignancies, thus paving the way for their develo...

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Detalles Bibliográficos
Autores principales: Edeline, Julien, Houot, Roch, Marabelle, Aurélien, Alcantara, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054411/
https://www.ncbi.nlm.nih.gov/pubmed/33874996
http://dx.doi.org/10.1186/s13045-021-01067-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054411/
https://www.ncbi.nlm.nih.gov/pubmed/33874996
http://dx.doi.org/10.1186/s13045-021-01067-5

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