Cargando…
WAPL orchestrates porcine oocyte meiotic progression via control of spindle assembly checkpoint activity
BACKGROUND: In mitotic cells, WAPL acts as a cohesin release factor to remove cohesin complexes from chromosome arms during prophase to allow the accurate chromosome segregation in anaphase. However, we have recently documented that Wapl exerts a unique meiotic function in the spindle assembly check...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054420/ https://www.ncbi.nlm.nih.gov/pubmed/33874950 http://dx.doi.org/10.1186/s12958-021-00740-1 |