Cargando…

WAPL orchestrates porcine oocyte meiotic progression via control of spindle assembly checkpoint activity

BACKGROUND: In mitotic cells, WAPL acts as a cohesin release factor to remove cohesin complexes from chromosome arms during prophase to allow the accurate chromosome segregation in anaphase. However, we have recently documented that Wapl exerts a unique meiotic function in the spindle assembly check...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Changyin, Miao, Yilong, Zhang, Xue, Xiong, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054420/
https://www.ncbi.nlm.nih.gov/pubmed/33874950
http://dx.doi.org/10.1186/s12958-021-00740-1