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4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice

BACKGROUND: Chronic brain inflammation has been implicated in the pathogenesis of various neurodegenerative diseases and disorders. For example, overexpression of pro-inflammatory cytokines has been associated with impairments in hippocampal-dependent memory. Lipopolysaccharide (LPS) injection is a...

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Detalles Bibliográficos
Autores principales: Rojas-Colón, Luis A., Dash, Pramod K., Morales-Vías, Fabiola A., Lebrón-Dávila, Madeline, Ferchmin, Pedro A., Redell, John B., Maldonado-Martínez, Geronimo, Vélez-Torres, Wanda I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054431/
https://www.ncbi.nlm.nih.gov/pubmed/33874954
http://dx.doi.org/10.1186/s12974-021-02136-9