Cargando…

Time-resolved proteomics profiling of the ciliary Hedgehog response

The primary cilium is a signaling compartment that interprets Hedgehog signals through changes of its protein, lipid, and second messenger compositions. Here, we combine proximity labeling of cilia with quantitative mass spectrometry to unbiasedly profile the time-dependent alterations of the ciliar...

Descripción completa

Detalles Bibliográficos
Autores principales: May, Elena A., Kalocsay, Marian, D’Auriac, Inès Galtier, Schuster, Patrick S., Gygi, Steven P., Nachury, Maxence V., Mick, David U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054476/
https://www.ncbi.nlm.nih.gov/pubmed/33856408
http://dx.doi.org/10.1083/jcb.202007207