Cargando…
Automated synthesis of prexasertib and derivatives enabled by continuous-flow solid-phase synthesis
Recent advances in end-to-end continuous-flow synthesis are rapidly expanding the capabilities of automated customized syntheses of small-molecule pharmacophores, resulting in considerable industrial and societal impacts; however, many hurdles persist that limit the number of sequential steps that c...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054510/ https://www.ncbi.nlm.nih.gov/pubmed/33875818 http://dx.doi.org/10.1038/s41557-021-00662-w |