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Zi Qi Decoction Alleviates Liver Fibrosis by Inhibiting the Toll-Like Receptor 4 (TLR4)-Related Nuclear Factor kappa b (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways

BACKGROUND: Hepatic stellate cells (HSCs) play a vital role in hepatic fibrogenesis. Our recent clinical study indicated that the Zi Qi decoction, a Traditional Chinese Medicine formula, exhibited good efficacy in alleviating liver fibrosis, but the underlying mechanism remains elusive. MATERIAL/MET...

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Detalles Bibliográficos
Autores principales: Zhou, Jingwen, Zhang, Xiaolong, Wan, Lingfeng, Yu, Jun, Li, Tianci, Lu, Ziyu, Fang, Nanyuan, Sun, Lixia, Ye, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054620/
https://www.ncbi.nlm.nih.gov/pubmed/33850093
http://dx.doi.org/10.12659/MSM.929438