Consequences of Mutations and Abnormal Expression of SMAD4 in Tumors and T Cells

SMAD4 is a typical tumor suppressor in the TGF-β signaling pathway. In human cancers, SMAD4 is frequently mutated and inactivated. In recent years, the consequences of mutations and inactivation of SMAD4 are gradually becoming clearer. Most of the mutations have negative consequences and reduce the...

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Detalles Bibliográficos
Autores principales: Wan, Rongxue, Feng, Jianguo, Tang, Liling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054659/
https://www.ncbi.nlm.nih.gov/pubmed/33888990
http://dx.doi.org/10.2147/OTT.S297855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054659/
https://www.ncbi.nlm.nih.gov/pubmed/33888990
http://dx.doi.org/10.2147/OTT.S297855

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