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TP53 mutation and MET amplification in circulating tumor DNA analysis predict disease progression in patients with advanced gastric cancer

BACKGROUND: Gastric cancer (GC) is a heterogeneous disease that encompasses various molecular subtypes. The molecular mutation characteristics of circulating tumor DNA (ctDNA) in advanced gastric cancer (AGC), especially the clinical utility of TP53 mutation and MET amplification in ctDNA need to be...

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Detalles Bibliográficos
Autores principales: Li, Jia, Li, Zhaoyan, Ding, Yajie, Xu, Yan, Zhu, Xiaohong, Cao, Nida, Huang, Chen, Qin, Mengmeng, Liu, Feng, Zhao, Aiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054733/
https://www.ncbi.nlm.nih.gov/pubmed/33959414
http://dx.doi.org/10.7717/peerj.11146