Integrated molecular drivers coordinate biological and clinical states in melanoma

We performed harmonized molecular and clinical analysis on 1,048 melanomas and discovered markedly different global genomic properties among subtypes (BRAF, (N)RAS, NF1, Triple Wild-Type), subtype-specific preferences for secondary driver genes, and active mutational processes previously unreported...

Descripción completa

Detalles Bibliográficos
Autores principales: Conway, Jake R., Dietlein, Felix, Taylor-Weiner, Amaro, AlDubayan, Saud, Vokes, Natalie, Keenan, Tanya, Reardon, Brendan, He, Meng Xiao, Margolis, Claire A., Weirather, Jason L., Haq, Rizwan, Schilling, Bastian, Hodi, F. Stephen, Schadendorf, Dirk, Liu, David, Van Allen, Eliezer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054830/
https://www.ncbi.nlm.nih.gov/pubmed/33230298
http://dx.doi.org/10.1038/s41588-020-00739-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054830/
https://www.ncbi.nlm.nih.gov/pubmed/33230298
http://dx.doi.org/10.1038/s41588-020-00739-1

Ejemplares similares