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An early cell shape transition drives evolutionary expansion of the human forebrain

The human brain has undergone rapid expansion since humans diverged from other great apes, but the mechanism of this human-specific enlargement is still unknown. Here, we use cerebral organoids derived from human, gorilla, and chimpanzee cells to study developmental mechanisms driving evolutionary b...

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Detalles Bibliográficos
Autores principales: Benito-Kwiecinski, Silvia, Giandomenico, Stefano L., Sutcliffe, Magdalena, Riis, Erlend S., Freire-Pritchett, Paula, Kelava, Iva, Wunderlich, Stephanie, Martin, Ulrich, Wray, Gregory A., McDole, Kate, Lancaster, Madeline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054913/
https://www.ncbi.nlm.nih.gov/pubmed/33765444
http://dx.doi.org/10.1016/j.cell.2021.02.050