Computational modelling of perivascular-niche dynamics for the optimization of treatment schedules for glioblastoma

Glioma stem-like cells dynamically transition between a chemoradiation-resistant state (preferentially in the perivascular niche) and a chemoradiation-sensitive state (away from blood vessels). However, physical barriers in the tumour microenvironment restrict the delivery of chemotherapy to tumour...

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Detalles Bibliográficos
Autores principales: Randles, Amanda, Wirsching, Hans-Georg, Dean, Jamie A., Cheng, Yu-Kang, Emerson, Samuel, Pattwell, Siobhan S., Holland, Eric C., Michor, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054983/
https://www.ncbi.nlm.nih.gov/pubmed/33864039
http://dx.doi.org/10.1038/s41551-021-00710-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054983/
https://www.ncbi.nlm.nih.gov/pubmed/33864039
http://dx.doi.org/10.1038/s41551-021-00710-3

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