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Mycobacterial infection-induced miR-206 inhibits protective neutrophil recruitment via the CXCL12/CXCR4 signalling axis

Pathogenic mycobacteria actively dysregulate protective host immune signalling pathways during infection to drive the formation of permissive granuloma microenvironments. Dynamic regulation of host microRNA (miRNA) expression is a conserved feature of mycobacterial infections across host-pathogen pa...

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Detalles Bibliográficos
Autores principales: Wright, Kathryn, de Silva, Kumudika, Plain, Karren M., Purdie, Auriol C., Blair, Tamika A., Duggin, Iain G., Britton, Warwick J., Oehlers, Stefan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055004/
https://www.ncbi.nlm.nih.gov/pubmed/33826679
http://dx.doi.org/10.1371/journal.ppat.1009186