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The RabGAP TBC-11 controls Argonaute localization for proper microRNA function in C. elegans

Once loaded onto Argonaute proteins, microRNAs form a silencing complex called miRISC that targets mostly the 3’UTR of mRNAs to silence their translation. How microRNAs are transported to and from their target mRNA remains poorly characterized. While some reports linked intracellular trafficking to...

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Detalles Bibliográficos
Autores principales: Michaud, Pascale, Shah, Vivek Nilesh, Adjibade, Pauline, Houle, Francois, Quévillon Huberdeau, Miguel, Rioux, Rachel, Lavoie-Ouellet, Camille, Gu, Weifeng, Mazroui, Rachid, Simard, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055011/
https://www.ncbi.nlm.nih.gov/pubmed/33826611
http://dx.doi.org/10.1371/journal.pgen.1009511