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The RabGAP TBC-11 controls Argonaute localization for proper microRNA function in C. elegans
Once loaded onto Argonaute proteins, microRNAs form a silencing complex called miRISC that targets mostly the 3’UTR of mRNAs to silence their translation. How microRNAs are transported to and from their target mRNA remains poorly characterized. While some reports linked intracellular trafficking to...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055011/ https://www.ncbi.nlm.nih.gov/pubmed/33826611 http://dx.doi.org/10.1371/journal.pgen.1009511 |