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Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion

To trigger gamete fusion, spermatozoa need to activate the molecular machinery in which sperm IZUMO1 and oocyte JUNO (IZUMO1R) interaction plays a critical role in mammals. Although a set of factors involved in this process has recently been identified, no common factor that can function in both ver...

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Detalles Bibliográficos
Autores principales: Inoue, Naokazu, Hagihara, Yoshihisa, Wada, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055269/
https://www.ncbi.nlm.nih.gov/pubmed/33871360
http://dx.doi.org/10.7554/eLife.66313