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Association of GBA Genotype With Motor and Functional Decline in Patients With Newly Diagnosed Parkinson Disease

OBJECTIVE: To establish the significance of glucocerebrosidase gene (GBA) carrier status on motor impairment in a large cohort of patients with incident Parkinson disease (PD). METHODS: Three European population-based studies followed 528 patients with PD from diagnosis. A total of 440 with genomic...

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Detalles Bibliográficos
Autores principales: Maple-Grødem, Jodi, Dalen, Ingvild, Tysnes, Ole-Bjørn, Macleod, Angus D., Forsgren, Lars, Counsell, Carl E., Alves, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055329/
https://www.ncbi.nlm.nih.gov/pubmed/33443131
http://dx.doi.org/10.1212/WNL.0000000000011411