Astragaloside IV Inhibits Mitochondrial-Dependent Apoptosis of the Dorsal Root Ganglion in Diabetic Peripheral Neuropathy Rats Through Modulation of the SIRT1/p53 Signaling Pathway

PURPOSE: To investigate the effect of astragaloside IV (AS-IV) on mitochondrial-dependent apoptosis in the dorsal root ganglion of diabetic peripheral neuropathy (DPN) rats through the SIRT1/p53 pathway. METHODS: Diabetic rat model was induced by high-carbohydrate/high-fat diet and intraperitoneal i...

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Detalles Bibliográficos
Autores principales: Ben, Ying, Hao, Juan, Zhang, Zhihong, Xiong, Yunzhao, Zhang, Cuijuan, Chang, Yi, Yang, Fan, Li, Hui, Zhang, Tianya, Wang, Xiangting, Xu, Qingyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055373/
https://www.ncbi.nlm.nih.gov/pubmed/33883914
http://dx.doi.org/10.2147/DMSO.S301068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055373/
https://www.ncbi.nlm.nih.gov/pubmed/33883914
http://dx.doi.org/10.2147/DMSO.S301068

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