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Astragaloside IV Inhibits Mitochondrial-Dependent Apoptosis of the Dorsal Root Ganglion in Diabetic Peripheral Neuropathy Rats Through Modulation of the SIRT1/p53 Signaling Pathway

PURPOSE: To investigate the effect of astragaloside IV (AS-IV) on mitochondrial-dependent apoptosis in the dorsal root ganglion of diabetic peripheral neuropathy (DPN) rats through the SIRT1/p53 pathway. METHODS: Diabetic rat model was induced by high-carbohydrate/high-fat diet and intraperitoneal i...

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Detalles Bibliográficos
Autores principales:	Ben, Ying, Hao, Juan, Zhang, Zhihong, Xiong, Yunzhao, Zhang, Cuijuan, Chang, Yi, Yang, Fan, Li, Hui, Zhang, Tianya, Wang, Xiangting, Xu, Qingyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055373/ https://www.ncbi.nlm.nih.gov/pubmed/33883914 http://dx.doi.org/10.2147/DMSO.S301068

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