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The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies

Although neutralizing monoclonal antibodies (mAbs) against epitopes within the alphavirus E2 protein can protect against infection, the functional significance of non-neutralizing mAbs is poorly understood. Here, we evaluate the activity of 13 non-neutralizing mAbs against Mayaro virus (MAYV), an em...

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Detalles Bibliográficos
Autores principales: Earnest, James T., Holmes, Autumn C., Basore, Katherine, Mack, Matthias, Fremont, Daved H., Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055377/
https://www.ncbi.nlm.nih.gov/pubmed/33826892
http://dx.doi.org/10.1016/j.celrep.2021.108962