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Follistatin-Like 1 Attenuation Suppresses Intervertebral Disc Degeneration in Mice through Interacting with TNF-α and Smad Signaling Pathway

BACKGROUND: Inflammation plays an important role in intervertebral disc degeneration (IDD). The protein follistatin-like 1 (FSTL1) plays a proinflammatory role in a variety of inflammatory diseases. OBJECTIVES: The purpose of this study was to investigate whether IDD could be delayed by inhibiting F...

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Detalles Bibliográficos
Autores principales: Wang, Shaoyi, Wei, Jianlu, Shi, Jie, He, Qiting, Zhou, Xiaocong, Gao, Ximei, Cheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055391/
https://www.ncbi.nlm.nih.gov/pubmed/33936382
http://dx.doi.org/10.1155/2021/6640751