Binding mechanism of naringenin with monoamine oxidase – B enzyme: QM/MM and molecular dynamics perspective

The reduced level of dopamine at midbrain (substantia nigra) leads to Parkinson disease by the influence of monoamine oxidation process of monoamine oxidase B (MAO-B) enzyme. This disease mostly affects the aged people. Reports outline that the naringenin molecule acts as an inhibitor of MAO-B enzym...

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Detalles Bibliográficos
Autores principales: Govindasamy, Hunday, Magudeeswaran, Sivanandam, Kandasamy, Saravanan, Poomani, Kumaradhas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055563/
https://www.ncbi.nlm.nih.gov/pubmed/33898820
http://dx.doi.org/10.1016/j.heliyon.2021.e06684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055563/
https://www.ncbi.nlm.nih.gov/pubmed/33898820
http://dx.doi.org/10.1016/j.heliyon.2021.e06684

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