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Binding mechanism of naringenin with monoamine oxidase – B enzyme: QM/MM and molecular dynamics perspective
The reduced level of dopamine at midbrain (substantia nigra) leads to Parkinson disease by the influence of monoamine oxidation process of monoamine oxidase B (MAO-B) enzyme. This disease mostly affects the aged people. Reports outline that the naringenin molecule acts as an inhibitor of MAO-B enzym...
Autores principales: | Govindasamy, Hunday, Magudeeswaran, Sivanandam, Kandasamy, Saravanan, Poomani, Kumaradhas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055563/ https://www.ncbi.nlm.nih.gov/pubmed/33898820 http://dx.doi.org/10.1016/j.heliyon.2021.e06684 |
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