Associations of TP53 codon 72 polymorphism with complications and comorbidities in patients with type 1 diabetes
ABSTRACT: Wild-type TP53 plays an important role in the regulation of immune response and systemic inflammation. In type 1 diabetes (T1D), TP53 pathways are upregulated and an increased susceptibility to apoptosis is observed. We hypothesize that TP53 codon 72 polymorphism could be associated with c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055568/ https://www.ncbi.nlm.nih.gov/pubmed/33495869 http://dx.doi.org/10.1007/s00109-020-02035-1 |