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Impaired in vitro growth response of plasma-treated cardiomyocytes predicts poor outcome in patients with transthyretin amyloidosis

OBJECTIVES: Direct toxic effects of transthyretin amyloid in patient plasma upon cardiomyocytes are discussed. However, no data regarding the relevance of this putative effect for clinical outcome are available. In this monocentric prospective study, we analyzed cellular hypertrophy after phenylephr...

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Detalles Bibliográficos
Autores principales: Hein, Selina, Furkel, Jennifer, Knoll, Maximilian, aus dem Siepen, Fabian, Schönland, Stefan, Hegenbart, Ute, Katus, Hugo A., Kristen, Arnt V., Konstandin, Mathias H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055573/
https://www.ncbi.nlm.nih.gov/pubmed/33481097
http://dx.doi.org/10.1007/s00392-020-01801-y