Induced pluripotent stem cells from subjects with Lesch-Nyhan disease

Lesch-Nyhan disease (LND) is an inherited disorder caused by pathogenic variants in the HPRT1 gene, which encodes the purine recycling enzyme hypoxanthine–guanine phosphoribosyltransferase (HGprt). We generated 6 induced pluripotent stem cell (iPSC) lines from 3 individuals with LND, along with 6 co...

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Detalles Bibliográficos
Autores principales: Sutcliffe, Diane J., Dinasarapu, Ashok R., Visser, Jasper E., Hoed, Joery den, Seifar, Fatemeh, Joshi, Piyush, Ceballos-Picot, Irene, Sardar, Tejas, Hess, Ellen J., Sun, Yan V., Wen, Zhexing, Zwick, Michael E., Jinnah, H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055678/
https://www.ncbi.nlm.nih.gov/pubmed/33875724
http://dx.doi.org/10.1038/s41598-021-87955-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055678/
https://www.ncbi.nlm.nih.gov/pubmed/33875724
http://dx.doi.org/10.1038/s41598-021-87955-9

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