JAC1 suppresses proliferation of breast cancer through the JWA/p38/SMURF1/HER2 signaling

The overexpression of HER2 is associated with a malignant proliferation of breast cancer. In this study, we developed a non-cytotoxic JWA gene activating compound 1 (JAC1) to inhibit the proliferation of HER2-positive breast cancer cells in vitro and in vivo experimental models. JAC1 increased the u...

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Detalles Bibliográficos
Autores principales: Ren, Yanlin, Chen, Dongyin, Zhai, Zurong, Chen, Junjie, Li, Aiping, Liang, Yan, Zhou, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055679/
https://www.ncbi.nlm.nih.gov/pubmed/33875644
http://dx.doi.org/10.1038/s41420-021-00426-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055679/
https://www.ncbi.nlm.nih.gov/pubmed/33875644
http://dx.doi.org/10.1038/s41420-021-00426-y

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