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JAC1 suppresses proliferation of breast cancer through the JWA/p38/SMURF1/HER2 signaling
The overexpression of HER2 is associated with a malignant proliferation of breast cancer. In this study, we developed a non-cytotoxic JWA gene activating compound 1 (JAC1) to inhibit the proliferation of HER2-positive breast cancer cells in vitro and in vivo experimental models. JAC1 increased the u...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055679/ https://www.ncbi.nlm.nih.gov/pubmed/33875644 http://dx.doi.org/10.1038/s41420-021-00426-y |