Curcumin activates Nrf2 through PKCδ-mediated p62 phosphorylation at Ser351

Curcumin, a phytochemical extracted from Curcuma longa rhizomes, is known to be protective in neurons via activation of Nrf2, a master regulator of endogenous defense against oxidative stress in cells. However, the exact mechanism by which curcumin activates Nrf2 remains controversial. Here, we obse...

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Detalles Bibliográficos
Autores principales: Park, Jee-Yun, Sohn, Hee-Young, Koh, Young Ho, Jo, Chulman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055680/
https://www.ncbi.nlm.nih.gov/pubmed/33875681
http://dx.doi.org/10.1038/s41598-021-87225-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055680/
https://www.ncbi.nlm.nih.gov/pubmed/33875681
http://dx.doi.org/10.1038/s41598-021-87225-8

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