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Curcumin activates Nrf2 through PKCδ-mediated p62 phosphorylation at Ser351
Curcumin, a phytochemical extracted from Curcuma longa rhizomes, is known to be protective in neurons via activation of Nrf2, a master regulator of endogenous defense against oxidative stress in cells. However, the exact mechanism by which curcumin activates Nrf2 remains controversial. Here, we obse...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055680/ https://www.ncbi.nlm.nih.gov/pubmed/33875681 http://dx.doi.org/10.1038/s41598-021-87225-8 |