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Multiplexed proteomic profiling of cysteine reactivity and ligandability in human T cells

Differential amino acid reactivity with chemical probes can provide valuable information on the functionality and ligandability of proteins in native biological systems. Here, we present a quantitative, multiplexed chemical proteomic protocol for in-depth reactivity and ligandability profiling of cy...

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Detalles Bibliográficos
Autores principales: Vinogradova, Ekaterina V., Cravatt, Benjamin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055706/
https://www.ncbi.nlm.nih.gov/pubmed/33899026
http://dx.doi.org/10.1016/j.xpro.2021.100458