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The tumor suppressor archipelago E3 ligase is required for spermatid differentiation in Drosophila testis

The human orthologue of the tumor suppressor protein FBW7 is encoded by the Drosophila archipelago (ago) gene. Ago is an F-box protein that gives substrate specificity to its SCF ubiquitin ligase complex. It has a central role in multiple biological processes in a tissue-specific manner such as cell...

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Detalles Bibliográficos
Autores principales: Vedelek, Viktor, Kovács, Attila L., Juhász, Gábor, Alzyoud, Elham, Sinka, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055871/
https://www.ncbi.nlm.nih.gov/pubmed/33875704
http://dx.doi.org/10.1038/s41598-021-87656-3