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The tumor suppressor archipelago E3 ligase is required for spermatid differentiation in Drosophila testis
The human orthologue of the tumor suppressor protein FBW7 is encoded by the Drosophila archipelago (ago) gene. Ago is an F-box protein that gives substrate specificity to its SCF ubiquitin ligase complex. It has a central role in multiple biological processes in a tissue-specific manner such as cell...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055871/ https://www.ncbi.nlm.nih.gov/pubmed/33875704 http://dx.doi.org/10.1038/s41598-021-87656-3 |