In silico drug repurposing for filarial infection predicts nilotinib and paritaprevir as potential inhibitors of the Wolbachia 5′-aminolevulinic acid synthase

Filarial infections affect millions of individuals and are responsible for some notorious disabilities. Current treatment options involve repeated mass drug administrations, which have been met with several challenges despite some successes. Administration of doxycycline, an anti-Wolbachia agent, ha...

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Detalles Bibliográficos
Autores principales: Kwarteng, Alexander, Asiedu, Ebenezer, Sylverken, Augustina, Larbi, Amma, Mubarik, Yusif, Apprey, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055890/
https://www.ncbi.nlm.nih.gov/pubmed/33875732
http://dx.doi.org/10.1038/s41598-021-87976-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055890/
https://www.ncbi.nlm.nih.gov/pubmed/33875732
http://dx.doi.org/10.1038/s41598-021-87976-4

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