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Immunogenicity and efficacy of mRNA COVID-19 vaccine MRT5500 in preclinical animal models

Emergency use authorization of COVID vaccines has brought hope to mitigate pandemic of coronavirus disease 2019 (COVID-19). However, there remains a need for additional effective vaccines to meet the global demand and address the potential new viral variants. mRNA technologies offer an expeditious p...

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Detalles Bibliográficos
Autores principales: Kalnin, Kirill V., Plitnik, Timothy, Kishko, Michael, Zhang, Jinrong, Zhang, Donghui, Beauvais, Adrien, Anosova, Natalie G., Tibbitts, Tim, DiNapoli, Josh, Ulinski, Gregory, Piepenhagen, Peter, Cummings, Sheila M., Bangari, Dinesh S., Ryan, Susan, Huang, Po-Wei D., Huleatt, James, Vincent, Deanne, Fries, Katherine, Karve, Shrirang, Goldman, Rebecca, Gopani, Hardip, Dias, Anusha, Tran, Khang, Zacharia, Minnie, Gu, Xiaobo, Boeglin, Lianne, Abysalh, Jonathan, Vargas, Jorel, Beaulieu, Angela, Shah, Monic, Jeannotte, Travis, Gillis, Kimberly, Chivukula, Sudha, Swearingen, Ron, Landolfi, Victoria, Fu, Tong-Ming, DeRosa, Frank, Casimiro, Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055913/
https://www.ncbi.nlm.nih.gov/pubmed/33875658
http://dx.doi.org/10.1038/s41541-021-00324-5