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Exosome-Mediated Delivery of the Neuroprotective Peptide PACAP38 Promotes Retinal Ganglion Cell Survival and Axon Regeneration in Rats With Traumatic Optic Neuropathy

Traumatic optic neuropathy (TON) refers to optic nerve damage caused by trauma, leading to partial or complete loss of vision. The primary treatment options, such as hormonal therapy and surgery, have limited efficacy. Pituitary adenylate cyclase-activating polypeptide 38 (PACAP38), a functional end...

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Detalles Bibliográficos
Autores principales: Wang, Tian, Li, Yiming, Guo, Miao, Dong, Xue, Liao, Mengyu, Du, Mei, Wang, Xiaohong, Yin, Haifang, Yan, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055942/
https://www.ncbi.nlm.nih.gov/pubmed/33889576
http://dx.doi.org/10.3389/fcell.2021.659783